The College of Science encourages students to join student government and interest organizations to broaden the scope of their student life in DLSU-D.
- College of Science Student Government (COSSG)
- Applied Mathematics Program Council (AMPC)
- Biological Science Program Council (BIOPC)
- Computer Science and Information Technology Program Council (CSITPC)
- DLSU-D Pre-Medical Society (DPMS)
- Lasallian First Aiders Red Cross Youth (LSFA-RCY)
- Lasallian Computer Society (LCS)