The cuarto or bedroom of the Museo de La Salle showcases the collections of Dr. Jaime Laya and the D.M. Guevara Foundation. In it are basic bedroom furniture and turn-of-the-century essential furnishings of houses such as four-poster beds draped with colgadura lace curtains, a cuna or baby crib, a mesa altar and a comoda. The Sandoval-Laya room is named after Alice Sandoval Laya, late wife of Dr. Jaime Laya.
Another cuarto features the DM Guevarra and Arnedo-Gonzalez collections of narra four-poster bed with carved head, feet and canopy. The pink bedroom also showcases the wall and ceiling hand-painting patterned after the Constantino House in Balagtas, Bulacan. The hand painting, specifically on the ceiling, features the “trompe l’oeil” technique manifested in the floating butterflies.